Carneiro, Bruno Hassunuma Breda, Giovanni Luis Cognialli, Regielly Caroline Raimundo Santos, Germana Davila dos Vicente, Vania Aparecida Perondi, Eduardo Gnoatto França, João Cesar Beenke Queiroz-Telles, Flávio
Cryptococcal disease is the third most common invasive fungal infection in solid organ transplant recipients and is associated with high-morbidity and -mortality rates. Donor-derived Cryptococcus spp. infection typically manifests within the first month post-procedure and has historically been caused by C. neoformans complex, predominantly in kidney recipients, but also after liver transplantation. We report the first documented case of donor-derived, early-onset C. gattii complex meningoencephalitis following liver transplantation in a 54-year-old woman, successfully treated with amphotericin B and fluconazole, and review the relevant literature.
Keywords: Cryptococcosis; C. gattii; Solid organ transplant