Humberto Menezes
Departamento de Genética e Matemática Aplicada à Biologia. Fac. Med. Rib. Preto, USP. 14.100, Ribeirão Preto. SP, Brasil
SUMMARY
The use of antilymphocytic serum (ALS) in dogs suppressed the immune response of a vacclnated and simultaneously ALS treated animal, increased the infectivity of a virulent strain and did not induce a typical infectian-disease in 3 dogs receiving the serum and the avirulent PF strain.
RESUMO
Soro antilinfocitário ALS anti-cão mostrou-se capaz de agravar uma infecção produzida pela cepa virulenta Y do Trypanosoma cruzi (Graph I, Table 4).
Cães vacinados com a cepa avirulenta PF não demonstraram, 9 meses após o início da experiência, qualquer sinal de infecção-doença, apesar das altas doses de soro recebidas (Graph I, Tables 1-3).
O soro é um poderoso imunosupressor capaz de impedir o desenvolvimento de defesas imunitárias em um animal injetado com a cepa PF e simultaneamente tratado com o mesmo (Table 6).
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REFERENCES
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